Incidence of Cerebral Microbleeds in the General Population

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Incidence of Cerebral Microbleeds in the General Population

Background and Purpose—Cerebral microbleeds are frequently seen in the general elderly population, but it is unknown at what rate they occur with aging and whether once present can disappear over time. Methods—As part of the Rotterdam Scan Study, 831 persons (mean age, 68.5 years) underwent repeated brain MRI with a mean interval of 3.4 years. We assessed determinants of incident microbleeds in...

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Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study.

BACKGROUND AND PURPOSE Cerebral microbleeds are frequently seen in the general elderly population, but it is unknown at what rate they occur with aging and whether once present can disappear over time. METHODS As part of the Rotterdam Scan Study, 831 persons (mean age, 68.5 years) underwent repeated brain MRI with a mean interval of 3.4 years. We assessed determinants of incident microbleeds ...

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Inhibition of serotonin reuptake by antidepressants and cerebral microbleeds in the general population.

BACKGROUND AND PURPOSE Serotonin reuptake inhibiting antidepressants decrease platelet aggregation. This may cause an increased risk of intracerebral hemorrhage. However, the risk of subclinical microbleeds, which are highly prevalent in middle-aged and elderly people, is unknown. We studied whether serotonin reuptake inhibiting antidepressants increase the frequency of cerebral microbleeds and...

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Use of coumarin anticoagulants and cerebral microbleeds in the general population.

BACKGROUND AND PURPOSE It remains undetermined whether the use of coumarin anticoagulants associates with cerebral microbleeds in the general population. We investigated whether (1) coumarin use relates to higher prevalence and incidence of microbleeds, (2) microbleeds are more frequent in people with higher maximum international normalized ratios (INRs), and (3) among coumarin users, variabili...

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Association Between Cerebral Microbleeds and Depression in the General Elderly Population: A Meta-Analysis

Background It remains unclear whether cerebral microbleeds (CMBs) are associated with depression in the general elderly population. We thus performed a meta-analysis to evaluate the relationship between depression and CMBs. Methods A systematic literature search was conducted in EBSCO, PubMed, and Web of Science for relevant studies that assessed the relationship between depression and the pr...

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ژورنال

عنوان ژورنال: Stroke

سال: 2011

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.110.607184